Retrograde memory enhancement and stress
Jun. 28th, 2006 06:52 pm![[personal profile]](https://www.dreamwidth.org/img/silk/identity/user.png){kind=small}
anhinga_draftsThere is too many notes related to 10th ICCNS conference to be made. So I'll probably keep them here and will make digests in the main journal once in a while.
Various retrograde amnesia effects are well known. James McGaugh of the University of California at Irvine demostrated the effects of retrograde memory enhancement if norepinephrine is increased after a learning experience (via stress or some other mechanism, like direct injection of norepinephrine or cortisol, or stimulation of the BLA (basolateral complex of the amygdala).
The retrograde enhancement effects are strongest if this is done with 30 minute after the learning experience, still noticeable if the delay is up to 2 hours.
BLA projects to a number of areas, including hippocampus, striatum, and cortical regions. McGaugh claims sex differences, that in females it's left amydgala, and in males it's right amygdala, which plays this role.
Somebody (I am not sure whether it was in this talk, or in a related talk), claimed that a more localized norepinephrine boost results in a more specialized memory enhancement, e.g. a boost to hippocampus only would do this selectively, namely for positional memory only.
An interview by the author for general public in 2003.
Or, and I finally understood where the term (nor)epinephrine came from (as a more standard English name for (nor)adrenaline) :-) Took me a "few years" :-)
Various retrograde amnesia effects are well known. James McGaugh of the University of California at Irvine demostrated the effects of retrograde memory enhancement if norepinephrine is increased after a learning experience (via stress or some other mechanism, like direct injection of norepinephrine or cortisol, or stimulation of the BLA (basolateral complex of the amygdala).
The retrograde enhancement effects are strongest if this is done with 30 minute after the learning experience, still noticeable if the delay is up to 2 hours.
BLA projects to a number of areas, including hippocampus, striatum, and cortical regions. McGaugh claims sex differences, that in females it's left amydgala, and in males it's right amygdala, which plays this role.
Somebody (I am not sure whether it was in this talk, or in a related talk), claimed that a more localized norepinephrine boost results in a more specialized memory enhancement, e.g. a boost to hippocampus only would do this selectively, namely for positional memory only.
An interview by the author for general public in 2003.
Or, and I finally understood where the term (nor)epinephrine came from (as a more standard English name for (nor)adrenaline) :-) Took me a "few years" :-)
no subject
Date: 2006-10-10 09:05 pm (UTC)It has been discovered millennia ago - that's what educational corporal punishment was for.
no subject
Date: 2006-10-10 09:12 pm (UTC)But the results indeed, rather unexpectedly, suggest that it also helps to recall what was just missed ! ;-)))